COL16A1 (collagen, type XVI, alpha 1)

Love, Truth and the Economy: A Reflection on Benedict XVI's Caritas in Veritate

COL 1 A 1 ( collagen , type I , alpha 1 )

Inhibition of collagen XVI expression reduces glioma cell invasiveness.

Glioblastomas are characterized by an intense local invasiveness that limits surgical resection. One mechanism by which glioma cells enforce their migration into brain tissue is reorganization of tumour associated extracellular matrix (ECM). Collagen XVI is a minor component of connective tissues. However, in glioblastoma tissue it is dramatically upregulated compared to the ECM of normal corte...

Expression and characterization of Xenopus type I collagen alpha 1 (COL1A1) during embryonic development.

A cDNA encoding Xenopus type I collagen alpha 1 (Xenopus COL1A1) has been isolated from an ovary cDNA library. The COL1A1 cDNA is approximately 5.7 kb pairs and encodes 1447 amino acids. The putative COL1A1 polypeptide shares high identities of amino acid sequence with other vertebrate COL1A1 proteins. The level of Xenopus COL1A1 transcripts was increased markedly in the posterior region of the...

The Mouse MC13 Mutant Is a Novel ENU Mutation in Collagen Type II, Alpha 1

Phenotype-driven mutagenesis experiments are a powerful approach to identifying novel alleles in a variety of contexts. The traditional disadvantage of this approach has been the subsequent task of identifying the affected locus in the mutants of interest. Recent advances in bioinformatics and sequencing have reduced the burden of cloning these ENU mutants. Here we report our experience with an...